The Road by Cormac McCarthy
Every horrible thing you think may happen at the start of The Road, Cormac McCarthy’s post-apocalyptic tour-de-force, does, in fact, happen. That’s not the upsetting part, though: what gets us is the fact that this annihilated reality could actually come to pass in our lifetime. There’s also the whole “the lengths a father/son bond will extend even throughout the most horrific situations” bit, too. With The Road, Cormac McCarthy made the threat of nuclear annihilation a family issue.